3^rd International Conference on Endocrinology and Metabolic Syndrome June 28-29, 2018 Amsterdam, Netherlands

Cardiovascular disease refers to more than one disease of the circulatory system including the heart and blood vessels, whether the blood vessels are affecting the lungs, the brain, kidneys or other parts of the body. Coronary artery disease, stroke, and peripheral artery disease involve atherosclerosis. This may be caused by high blood pressure, smoking, diabetes, lack of exercise, obesity, high blood cholesterol, poor diet, and excessive alcohol consumption, among others.

Polycystic ovary syndrome (PCOS) is associated with higher prevalence of cardiovascular risk factors but the relative prevalence of cardiovascular disease in women with PCOS has not previously been reported. High blood pressure results in 13% of CVD deaths, while tobacco results in 9%, diabetes 6%, lack of exercise 6% and obesity 5%. The effect of the use of aspirin in people who are otherwise healthy is of unclear benefit. Treatment of those who have CVD improves outcomes. Cardiovascular diseases are the leading cause of death globally. Coronary artery disease and stroke account for 80% of CVD deaths in males and 75% of CVD deaths in females. Most cardiovascular disease affects older adults.

Endocrine glands are a group of glands in the body which secrete hormones. The endocrine system influences how your heart beats, how your bones and tissues grow, even your ability to make a baby. It plays a vital role in whether or not you develop diabetes, thyroid disease, growth disorders, sexual dysfunction, and a host of other hormone-related disorders. Endocrine disorders are typically grouped into two categories:

• Endocrine disease that results when a gland produces too much or too little of an endocrine hormone, called a hormonal imbalance.
• Endocrine disease due to the development of lesions (such as nodules or tumours) in the endocrine system, which may or may not affect on hormone levels.

Being overweight or obese predisposes an individual to many medical problems including diabetes, high blood pressure, heart disease, stroke, depression and some types of cancer. Endocrinologists work closely with dieticians, exercise physiologists, behavioural therapists and bariatric surgeons as part of the Comprehensive Weight Loss Centre to help patients achieve realistic weight-loss goals and improve health.

Paediatric Endocrinology is a medical subspecialty dealing with disorders of the endocrine glands, such as variations of physical growth and sexual development in childhood, diabetes and many more. The most common disease of the specialty is type 1 diabetes, which usually accounts for at least 50% of a typical clinical practice. Type 2 diabetes is a long haul metabolic turmoil that is portrayed by high glucose, insulin resistance, and relative absence of insulin. Basic side effects incorporate expanded thirst, incessant pee, and unexplained weight reduction. Indications may likewise incorporate expanded craving, feeling tired, and bruises that don't recuperate. The next most common problem is growth disorders, especially those amenable to growth hormone treatment. Pediatric endocrinologists are usually the primary physicians involved in the medical care of infants and children with intersex disorders. The specialty also deals with hypoglycemia and other forms of hyperglycemia in childhood, variations of puberty, as well other adrenal, thyroid, and pituitary problems. Many pediatric endocrinologists have interests and expertise in bone metabolism, lipid metabolism, adolescent gynecology, or inborn errors of metabolism.

Oxidative stress results due to disturbed equilibrium between pro-oxidants and antioxidants and plays a role in pathophysiology of Diabetes and Cardiovascular diseases. Obesity and its comorbidities, including type 2 diabetes mellitus and cardiovascular disease, are associated with a state of chronic low-grade inflammation that can be detected both systemically and within specific tissues. Areas of active investigation focus on the molecular bases of metabolic inflammation and potential pathogenic roles in insulin resistance, diabetes, and cardiovascular disease. An increased accumulation of macrophages occurring in obese adipose tissue has emerged as a key process in metabolic inflammation. Apparently, metabolic overload evokes stress reactions, such as oxidative, inflammatory, organelle and cell hypertrophy, generating vicious cycles. Adipocyte hypertrophy, through physical reasons, facilitates cell rupture, what will evoke an inflammatory reaction.

Diabetes is one of the most challenging health problems in the 21st century and one of the most common non-communicable diseases globally. It is the 4th or 5th leading cause of death in most high-income countries, with ~366 million diabetics in 2011 and an estimated 552 million in 2030. On the other hand, obesity has also become a world-wide epidemic. Obesity is a risk factor for the development of insulin resistance, with pancreatic beta cells compensating for insulin resistance by augmenting insulin secretion. The failure of beta-cells is believed to cause pre-diabetes, a condition that can lead to diabetes.  Approximately 85% of people with diabetes are type 2, and of these, 90% are obese or overweight. Diabetes & obesity are major contributors to various other chronic diseases such as coronary artery diseases, myocardial infarction, hypertension, dyslipidemia and a number of other complicated disorders mounting evidence shows that a Mediterranean style-diet may be useful in preventing and treating chronic diseases related to mild chronic inflammation such as visceral (abdominal) obesity, metabolic syndrome, and Type 2 diabetes.

Nutrition & Metabolism focuses on the integration of nutrition, exercise physiology, clinical investigations, and molecular and cellular biochemistry of metabolism. The areas of interest of Nutrition & Metabolism encompass studies in obesity, diabetes, lipidemias, metabolic syndrome and exercise physiology that have an underlying basis in metabolism. Metabolic effects of dietary protein are complex. In persons with type 2 diabetes, protein ingestion results in little or no increase in plasma glucose concentrations but a stimulation of insulin and glucagon secretion. The nutritional requirements of a neonate are significantly greater than those of an adult because not only are there requirements for substrate intake to fulfil basic metabolic needs, but there are metabolic needs to maintain rapid and continued growth and development.

The things that make you more likely to develop metabolic syndrome include Insulin resistance. A hormone disorder such as polycystic ovary syndrome (PCOS), a condition in which the female body produces too much of certain hormones, is associated with metabolic syndrome. In the metabolic syndrome (MS), a condition that associates three or more pathologies such as hypertension, central obesity, type II diabetes, insulin resistance and dyslipidemias, the kidneys are severely affected. The pathological alterations in the kidneys, associated with Metabolic Syndrome, may be modified by sex hormone levels.

Reproductive endocrinologist is a very important part of obstetrics and gynaecology in which physician is trained in reproductive medicine explaining about hormonal functioning as it indirectly relate to reproduction. Reproductive endocrinologist first focus on treatment of reproductive system. They are trained to evaluate and treat malfunctioning in females and males outside infertility. Reproductive endocrinologists have special training in obstetrics and gynaecology before they undergo sub-specialty training in Reproductive endocrinology and infertility.

Reproductive endocrinology and infertility is a surgical subspecialty of obstetrics and gynaecology that trains physicians in reproductive medicine addressing hormonal functioning as it pertains to reproduction as well as the issue of infertility. While most reproductive endocrinology and infertility specialists primarily focus on the treatment of infertility, reproductive endocrinologists are trained to also evaluate and treat hormonal dysfunctions in females and males outside infertility.

Clinical study aims directly improve global health outcomes and share clinical knowledge using case reports to convey important best practice messages. If case study is done then the advanced medical technologies like Transplantation, holistic treatment can be used more rapidly in hospitals and with the more study in Glycemic index and load  we can find the diseases or problem like Cortisol . Clinical case study done in medical diabetes could leads to find innovative way for treating the diabetes. Endocrine surgeons and Endocrinologists typically work closely together to provide the most advantageous care to patients afflicted with endocrine disorders.

Novel remedial targets accessible for diabetes incorporates Incretion based treatments, oral helpful operators like secretagogues, beta cell recovery and expansion and foundational microorganism treatments. Embryonic undeveloped cell and fetal antecedent cell transplantation treatments are the significant undifferentiated cell treatments accessible for Diabetes. Aside from the above, different computational methodologies in Diabetes administration control have been presented as of late which are assuming an imperative part in recognizable proof of qualities bringing about diabetes helping in Early Detection of Diabetes. These procedures are likewise valuable in concentrating on the compound etiologist of Diabetes revealing different treatment prospects and model development forms for survival expectation.

The World Health Organization require the presence of any one of diabetes mellitus, impaired glucose tolerance, impaired fasting glucose or insulin resistance. The European Group for the Study of Insulin Resistance requires insulin resistance defined as the top 25% of the fasting insulin values among non-diabetic individuals.

Endocrinology and Metabolic disorders are inherited genetic defects that interfere with the body’s metabolism, or the process by which the body gets energy from food. Symptoms vary from syndrome to syndrome, but often include developmental delays, vision and hearing problems, loss of intellectual function, muscle weakness, seizures, abnormal movements, stunted growth, pain and shortened life span. A successful bone marrow or stem cell transplant may help slow or halt the progression of certain syndromes, but early diagnosis is critical to prevent irreversible disease progression.

Various Diabetes and Endocrinology Center was established to improve the quality of life for people with diabetes and other endocrinology disorders. For diabetes patients, complications and sufferings contribute to the ultimate prevention and cure. For patients with other endocrinology disorders, including nodules in the endocrine system. New technologies have been developed to prevent everyone from the Metabolic Syndromes.

Energy metabolism is the process of generating energy (ATP) from nutrients. Metabolism comprises a series of interconnected pathways that can function in the presence or absence of oxygen. Aerobic metabolism converts one glucose molecule into 30-32 ATP molecules. The syndrome is thought to be caused by an underlying disorder of energy utilization and storage.

The best way to manage your stress is to learn healthy coping strategies. You can start practicing these tips right away. Try one or two until you find a few that work for you. Practice these techniques until they become habits you turn to when you feel stress. You can also use this coping strategies form to see how you respond to stress. Stress-relief techniques focus on relaxing your mind and your body.

Ways to relax your mind

• Write
• Let your feelings out
• Do something you enjoy
• Focus on the present
• Meditate

Muscle cell needs a lot of energy, which means they burn a lot of calories. In fact, they burn more calories than fat cells, even when you're not exercising. So the time you spend working out reaps benefits long after you stop sweating. Exercise becomes even more important as you get older. You naturally lose muscle mass with age, which slows down your metabolism. Working out can stop that slide.

Healthy eating is one of the best things you can do to prevent and control health problems such as heart disease, high blood pressure, type 2 diabetes, and some types of cancer. Weight management is a long-term approach to a healthy lifestyle. It includes a balance of healthy eating and physical exercise to equate energy expenditure and energy intake. Developing healthy eating habits while using tips that will keep us fuller longer can be useful tools in weight management. Knowing what your body needs is important to weight management and can control over consumption and under consumption of food. Weight management does not include fad diets that promote quick, temporary weight loss. It focuses on the long-term results that are achieved through slow weight loss, followed by retention of an ideal body weight for age, sex and height.

Herbal and alternative remedies have been utilized for health and restorative purposes for a few a great many years, majority of people still using herbal medicine to meet their wellbeing needs. Herbal supplements for the treatment of Hormonal Problems such as  Estrogen and Progesterone in Women and Treatment for menopausal Hormone Imbalance, etc. Homeopathy is a technique for treating disease by medications, given in moment dosages that would deliver in sound individual indications like those of the illness.